MITIN is proposing to elucidate the interplay between the insulin signaling pathway and the mitochondrial function

Prof. Antonio Zorzano

Antonio Zorzano

Contact e-mail

antonio.zorzanoarrobairbbarcelona.org

Background

Antonio Zorzano, Head of the Program of Molecular Medicine at the IRB (2002-present), and Professor of Biochemistry and Molecular Biology, Department of Biochemistry and Molecular Biology at the University of Barcelona (1991-present). He has over 20 years of experience focusing on the molecular genetics and regulation of metabolic processes involved in glucose uptake and signalling, especially with application to type 2 diabetes and obesity and their therapeutic intervention. He has published more than 170 original articles and chapters and is author of a number of seminal papers, and he is co-inventor of 11 patents most of them under industrial exploitation. He was one of the first to elucidate the novel regulation of cellular glucose transporters by insulin, a critical finding, and he has discovered that proteins involved in mitochondrial dynamics have an impact on cellular metabolism.

Selected publications

  1. A. Abella, L. Marti, M. Camps, M. Claret, J. Fernández-Alvarez, R. Gomis, A. Gumà, N. Viguerie, C. Carpéné, M. Palacín, X. Testar, A. Zorzano. Diabetes 52, 1004-1013, 2003.
  2. S. Pich, D. Bach, P. Briones, M. Liesa, M. Camps, X. Testar, M. Palacín, A. Zorzano. Human Mol. Genet 14, 1405-1415, 2005.
  3. D. Bach, D. Naon, S. Pich, F.X. Soriano, J. Rieusset, N. Vega, M. Laville, C. Guillet, Y. Boirie, H. Wallberg-Henriksson, M. Manco, M. Calvani, M. Castagneto, M. Palacín, G. Mingrone, J. R. Zierath, H. Vidal, A. Zorzano. Diabetes 54, 2685-2693, 2005.
  4. F.X. Soriano, M. Liesa, D. Bach, D.C. Chan, M. Palacín, A. Zorzano. Diabetes 55, 1783-1791, 2006.
  5. García-Vicente S., Yraola F., Marti L., González-Muñoz E., García-Barrado M.J., Cantó C., Abella A., Bour S., Artuch R., Sierra C., Brandi N., Carpéné C., Moratinos J., Camps M., Palacín M., Testar X., Gumà A., Albericio F., Royo M., Mian A.., Zorzano A.. Diabetes 56, 486-493, 2007

Research Group's Websites